VP (versatile peroxidases, EC 1.11.1.16) secreted by white‐rot fungi are involved in natural decay of lignin. VP combine the general catalytic features of other haem‐containing enzymes (in terms of substrate specificity and reaction mechanisms), such as the high‐redoxpotential
ligninolytic peroxidases, LiP (lignin peroxidase) and MnP (manganese peroxidase), with those of peroxidases with a lower redox potential, such as HRP (horseradish peroxidase)
and CiP (Coprinopsis cinerea peroxidase). Thus VP behaves as a generalist biocatalyst, readily oxidizing a variety of compounds.